战略投资 $6500万
2019-02-25关于我们
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$ 20.76
+1.08(5.49%)
04-24 16:08
Voyager Therapeutics
最高:20.95 | 今开:19.69 | 成交量:24.04万股 | 换手:0.65% |
最低:19.62 | 昨收:19.68 | 成交额:489.08万 | 振幅:6.73% |
52周最高:24.24 | 量比:0.65 | 市盈率(TTM):亏损 | 市净率:14.42 |
52周最低:7.76 | 委比:-81.82% | 市盈率(静):亏损 | 市销率:89.79 |
每股收益:-2.75 | 股息:-- | 每手股数:1 | 总市值:7.65亿 |
每股净资产:1.44 | 股息率:-- | 最小价差:0.01 | 总股本:3683.06万 |
机构持股:-- | Beta:2.83 | 空头回补天数:3.07 | 货币单位:USD |
战略投资 $6500万
2019-02-25
单位:美元
|
2018-06-30
|
2018-03-31
|
2017-12-31
|
2017-09-30
|
2017-06-30
|
流动资产
|
2.00亿
|
2.21亿
|
1.72亿
|
1.28亿
|
1.45亿
|
现金及短期投资
|
1.96亿
|
2.18亿
|
1.69亿
|
1.26亿
|
1.41亿
|
短期应收账款
|
--
|
--
|
145.20万
|
--
|
--
|
存货
|
--
|
--
|
--
|
--
|
--
|
其他流动资产
|
412.20万
|
243.30万
|
128.60万
|
260.40万
|
340.30万
|
非流动资产
|
1,441.80万
|
1,439.50万
|
1,268.70万
|
1,272.40万
|
1,368.80万
|
厂房及设备净资产
|
1,224.40万
|
1,145.80万
|
1,028.30万
|
1,055.80万
|
1,067.40万
|
项目总投资及垫款
|
159.50万
|
132.00万
|
180.00万
|
96.00万
|
148.00万
|
长期应收票据
|
--
|
--
|
--
|
--
|
--
|
无形资产
|
--
|
--
|
--
|
--
|
--
|
递延所得税资产
|
--
|
--
|
--
|
--
|
--
|
其他资产
|
57.90万
|
161.70万
|
60.40万
|
120.60万
|
153.40万
|
合计总资产
|
2.15亿
|
2.35亿
|
1.84亿
|
1.41亿
|
1.58亿
|
流动负债
|
2,909.50万
|
3,094.00万
|
1,589.70万
|
2,094.10万
|
1,183.60万
|
短期债务(含部分LTD)
|
--
|
--
|
--
|
--
|
--
|
应付账款
|
155.80万
|
137.20万
|
102.00万
|
91.10万
|
30.70万
|
应付所得税
|
--
|
--
|
--
|
--
|
--
|
其他流动负债
|
2,753.70万
|
2,956.80万
|
1,487.70万
|
2,003.00万
|
1,152.90万
|
非流动负债
|
1.04亿
|
1.06亿
|
3,452.90万
|
3,476.80万
|
4,128.70万
|
长期负债
|
--
|
--
|
--
|
--
|
--
|
拨备风险及费用
|
--
|
--
|
--
|
--
|
--
|
递延所得税负债
|
--
|
--
|
--
|
--
|
--
|
其他负债
|
1.04亿
|
1.06亿
|
3,452.90万
|
3,476.80万
|
4,128.70万
|
合计总负债
|
1.33亿
|
1.37亿
|
5,042.60万
|
5,570.90万
|
5,312.30万
|
股东权益合计
|
8,197.20万
|
9,829.30万
|
1.34亿
|
8,520.60万
|
1.05亿
|
非股权储备
|
--
|
--
|
--
|
--
|
--
|
优先股-账面价值
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
普通股权益(合计)
|
8,197.20万
|
9,829.30万
|
1.34亿
|
8,520.60万
|
1.05亿
|
累计少数股东权益
|
--
|
--
|
--
|
--
|
--
|
权益总额
|
8,197.20万
|
9,829.30万
|
1.34亿
|
8,520.60万
|
1.05亿
|
负债与股东权益合计
|
2.15亿
|
2.35亿
|
1.84亿
|
1.41亿
|
1.58亿
|
每股账面价值
|
2.56
|
3.08
|
4.25
|
3.25
|
4.05
|
每股账面价值-有形
|
2.56
|
3.08
|
4.25
|
3.25
|
4.05
|
单位:美元
|
2018-06-30
|
2018-03-31
|
2017-12-31
|
2017-09-30
|
2017-06-30
|
营业总收入
|
257.50万
|
94.20万
|
634.50万
|
114.80万
|
117.70万
|
-营业成本
|
257.50万
|
94.20万
|
634.50万
|
114.80万
|
117.70万
|
毛利
|
--
|
--
|
--
|
--
|
--
|
-销售管理及行政费用
|
2,775.30万
|
2,157.90万
|
1,825.70万
|
2,407.00万
|
1,940.70万
|
-其他运营费用
|
--
|
--
|
--
|
--
|
--
|
计息税前利润
|
-2,569.40万
|
-2,109.30万
|
-1,234.80万
|
-2,335.50万
|
-1,863.90万
|
+非经营收入(支出)
|
15.30万
|
98.70万
|
55.00万
|
30.90万
|
-4.20万
|
-非经常性支出
|
--
|
--
|
--
|
30.00万
|
--
|
-利息支出
|
--
|
--
|
--
|
--
|
--
|
税前净利润
|
-2,554.10万
|
-2,010.60万
|
-1,179.80万
|
-2,334.60万
|
-1,868.10万
|
-所得税
|
--
|
-18.00万
|
-3.10万
|
--
|
19.50万
|
+其他税后调整
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
+联署公司盈利权益
|
--
|
--
|
--
|
--
|
--
|
合并净利润
|
-2,554.10万
|
-1,992.60万
|
-1,176.70万
|
-2,334.60万
|
-1,887.60万
|
-少数股东权益开支
|
--
|
--
|
--
|
--
|
--
|
净利润
|
-2,554.10万
|
-1,992.60万
|
-1,176.70万
|
-2,334.60万
|
-1,887.60万
|
-优先股股息
|
--
|
--
|
--
|
--
|
--
|
一般可用收入净利润
|
-2,554.10万
|
-1,992.60万
|
-1,176.70万
|
-2,334.60万
|
-1,887.60万
|
每股基本收益
|
-0.80
|
-0.63
|
-0.40
|
-0.89
|
-0.73
|
摊薄每股收益
|
-0.80
|
-0.63
|
-0.40
|
-0.89
|
-0.73
|
息税折旧摊销前利润
|
-2,517.80万
|
-2,063.70万
|
-1,191.20万
|
-2,292.20万
|
-1,823.00万
|
单位:美元
|
2017-12-31
|
2016-12-31
|
2015-12-31
|
2014-12-31
|
净收益
|
-7,069.80万
|
-4,019.30万
|
-2,967.20万
|
-1,631.70万
|
+折旧损耗及摊稍
|
159.50万
|
61.20万
|
60.00万
|
18.40万
|
+递延税及投资税减免
|
--
|
--
|
--
|
--
|
+其他经营基金
|
937.30万
|
889.70万
|
1,395.20万
|
296.80万
|
营运资金
|
-5,973.00万
|
-3,068.40万
|
-1,512.00万
|
-1,316.50万
|
+特别项目
|
--
|
--
|
--
|
--
|
+营运资金变动
|
-162.00万
|
-1,179.80万
|
5,641.90万
|
124.70万
|
经营现金流
|
-6,135.00万
|
-4,248.20万
|
4,129.90万
|
-1,191.80万
|
资本支出
|
-398.50万
|
-502.90万
|
-103.00万
|
-298.80万
|
收购所得净资产
|
--
|
--
|
--
|
--
|
固定资产和业务出售收入
|
--
|
--
|
--
|
--
|
投资买卖净额
|
30.40万
|
5,232.90万
|
-1.94亿
|
--
|
非现金项目
|
0.00
|
0.00
|
0.00
|
-31.40万
|
投资现金流
|
-368.10万
|
4,730.00万
|
-1.95亿
|
-330.20万
|
发放现金股利
|
--
|
--
|
--
|
--
|
股本变动
|
5,992.00万
|
51.40万
|
1.05亿
|
2,212.00万
|
发行/削减债务净额
|
--
|
--
|
--
|
--
|
其他融资基金
|
--
|
--
|
7,295.50万
|
--
|
筹资现金流
|
5,992.00万
|
51.40万
|
1.78亿
|
2,212.00万
|
汇率影响
|
--
|
--
|
--
|
--
|
杂项基金
|
--
|
--
|
--
|
--
|
现金净流动
|
-511.10万
|
533.20万
|
2,427.40万
|
690.00万
|
自由现金流
|
-6,533.50万
|
-4,751.10万
|
4,026.90万
|
-1,490.60万
|
Steven Marc Paul
|
Steven Marc Paul founded SAGE Therapeutics, Inc. and Tal Medical, Inc. Currently, Dr. Paul is Chairman & Chief Executive Officer for Karuna Pharmaceuticals, Inc. and Executive Chairman for Tal Medical, Inc. He is also Member of Institute of Medicine, Member of National Academy of Sciences, Member of The National Advisory Mental Health Council and Member-Science Board at US Food & Drug Administration and on the board of 13 other companies.
Steven Marc Paul previously was Executive Vice President-Science & Technology at Eli Lilly & Co. President at Lilly Research Laboratories and Executive Vice President-Science & Technology at Lilly Industries Ltd. (both are subsidiaries of Eli Lilly & Co.), Medical Director-Commissioned Corps at US Public Health Service, Venture Partner at Third Rock Ventures LLC, Director at BioCrossroads, Scientific Director at National Institute of Mental Health, Member-Advisory Council at National Institute of General Medical Sciences and Professor at Weill Cornell Medical College.
Steven Marc Paul received an undergraduate degree from Tulane University (Louisiana) and a doctorate and a graduate degree from Tulane University School of Medicine.
|
Perry A. Karsen
|
Perry A. Karsen is a businessperson who has been the head of 8 different companies and currently occupies the position of Executive Chairman for OncoMed Pharmaceuticals, Inc., Chairman for Jounce Therapeutics, Inc., Chairman of Intellia Therapeutics, Inc. and President & Director at Stalar 3, Inc. Mr. Karsen is also on the board of Life Science Foundation, Gladstone Foundation (CA), Voyager Therapeutics, Inc. and The Sonoma Land Trust and Member of Roche Holding AG.
In his past career Mr. Karsen was Chairman at Pliant Therapeutics, Inc., Chief Operating Officer & Executive Vice President at Celgene Corp. Chief Executive Officer at Anthrogenesis Corp. Chief Executive Officer of Celgene Cellular Therapeutics and Chief Operations Officer & EVP at Celgene LLC (which are all subsidiaries of Celgene Corp.), General Partner for FirstMark Capital LLC, Senior VP & Head-Worldwide Business Development at Celgene Corp. Chief Executive Officer of Anthrogenesis Corp. Chief Executive Officer at Celgene Cellular Therapeutics and Chief Operations Officer & EVP at Celgene LLC (which are all subsidiaries of Celgene Corp.), VP-Strategic Business Analysis & Development at Bristol-Myers Squibb Co., Commercial Director-Europe Region at Abbott Laboratories, Venture Partner at Third Rock Ventures LLC, President & Chief Executive Officer for Pearl Therapeutics, Inc., Senior Vice President-Business Development at Human Genome Sciences, Inc., Director-Business Development at Genentech, Inc. and Senior Vice President-Sales & Marketing at Zimmer, Inc.
Perry A. Karsen received a graduate degree from Duke University, an undergraduate degree from the University of Illinois and an MBA from Kellogg School of Management.
|
Wendy L. Dixon
|
Currently, Wendy L. Dixon occupies the position of Chairman at Sesen Bio, Inc. and President at Great Meadow Consulting LLC. She is also on the board of 5 other companies.
In her past career Dr. Dixon occupied the position of Principal at West Pharmaceutical Services, Inc., Senior Vice President & President-Marketing at Merck & Co., Inc., Chief Marketing Officer for Bristol-Myers Squibb Co., Principal at Centocor, Inc., Senior Advisor at The Monitor Group, Inc., Principal at Osteotech, Inc. and Principal at Smithkline & French Laboratories US, Inc.
She received a graduate degree, a doctorate and an undergraduate degree from the University of Cambridge.
|
Mark Jay Levin
|
Mr. Mark J. Levin is a Chairman at Voyager Therapeutics, Inc., a Partner at Third Rock Ventures LLC, a Chairman at Fulcrum Therapeutics, Inc., a Managing Member at TRV GP LLC, a Member at National Academy of Engineering and a Member at Personalized Medicine Coalition. He is on the Board of Directors at Corvia Medical, Inc., NinePoint Medical, Inc. and Partners In Health.
Mr. Levin was previously employed as an Independent Director by Foundation Medicine, Inc., a Chief Executive Officer & Director by Millennium Pharmaceuticals, Inc., a Chief Executive Officer by Focal, Inc., a Chief Executive Officer by Tularik, Inc., a Chief Executive Officer by CytoTherapuetics, Inc., a Chief Executive Officer by StemCells, Inc., a Chief Executive Officer by Cell Genesys, Inc., a Partner by Mayfield Fund LLC, a Chief Executive Officer by Abgenix, Inc., a Chairman by Constellation Pharmaceuticals, Inc., a Process Engineer & Project Leader by Eli Lilly & Co., and a Process Engineer & Project Leader by Genentech, Inc. He also served on the board at Blueprint Medicines Corp. and Eleven Biotherapeutics, Inc.
He received his graduate degree from Washington University in St. Louis.
|
Michael John Higgins
|
Michael John Higgins is on the board of Genocea Biosciences, Inc. and 5 other companies.
In his past career he was Chief Operating Officer for Ironwood Pharmaceuticals, Inc., Chief Financial Officer for Boston Business Journal, Group Vice President at Jacobs Engineering Group, Inc. and Director & Vice President at Jacobs One Ltd. (a subsidiary of Jacobs Engineering Group, Inc.), Vice President-Finance & Business Development at Genzyme Corp. and Chief Financial Officer of Procept, Inc.
Mr. Higgins received an undergraduate degree from Cornell University, an MBA from Tuck School of Business at Dartmouth and a graduate degree from Dartmouth College.
|
Steven Marc Paul
|
Steven Marc Paul founded SAGE Therapeutics, Inc. and Tal Medical, Inc. Currently, Dr. Paul is Chairman & Chief Executive Officer for Karuna Pharmaceuticals, Inc. and Executive Chairman for Tal Medical, Inc. He is also Member of Institute of Medicine, Member of National Academy of Sciences, Member of The National Advisory Mental Health Council and Member-Science Board at US Food & Drug Administration and on the board of 13 other companies.
Steven Marc Paul previously was Executive Vice President-Science & Technology at Eli Lilly & Co. President at Lilly Research Laboratories and Executive Vice President-Science & Technology at Lilly Industries Ltd. (both are subsidiaries of Eli Lilly & Co.), Medical Director-Commissioned Corps at US Public Health Service, Venture Partner at Third Rock Ventures LLC, Director at BioCrossroads, Scientific Director at National Institute of Mental Health, Member-Advisory Council at National Institute of General Medical Sciences and Professor at Weill Cornell Medical College.
Steven Marc Paul received an undergraduate degree from Tulane University (Louisiana) and a doctorate and a graduate degree from Tulane University School of Medicine.
|
Perry A. Karsen
|
Perry A. Karsen is a businessperson who has been the head of 8 different companies and currently occupies the position of Executive Chairman for OncoMed Pharmaceuticals, Inc., Chairman for Jounce Therapeutics, Inc., Chairman of Intellia Therapeutics, Inc. and President & Director at Stalar 3, Inc. Mr. Karsen is also on the board of Life Science Foundation, Gladstone Foundation (CA), Voyager Therapeutics, Inc. and The Sonoma Land Trust and Member of Roche Holding AG.
In his past career Mr. Karsen was Chairman at Pliant Therapeutics, Inc., Chief Operating Officer & Executive Vice President at Celgene Corp. Chief Executive Officer at Anthrogenesis Corp. Chief Executive Officer of Celgene Cellular Therapeutics and Chief Operations Officer & EVP at Celgene LLC (which are all subsidiaries of Celgene Corp.), General Partner for FirstMark Capital LLC, Senior VP & Head-Worldwide Business Development at Celgene Corp. Chief Executive Officer of Anthrogenesis Corp. Chief Executive Officer at Celgene Cellular Therapeutics and Chief Operations Officer & EVP at Celgene LLC (which are all subsidiaries of Celgene Corp.), VP-Strategic Business Analysis & Development at Bristol-Myers Squibb Co., Commercial Director-Europe Region at Abbott Laboratories, Venture Partner at Third Rock Ventures LLC, President & Chief Executive Officer for Pearl Therapeutics, Inc., Senior Vice President-Business Development at Human Genome Sciences, Inc., Director-Business Development at Genentech, Inc. and Senior Vice President-Sales & Marketing at Zimmer, Inc.
Perry A. Karsen received a graduate degree from Duke University, an undergraduate degree from the University of Illinois and an MBA from Kellogg School of Management.
|
Wendy L. Dixon
|
Currently, Wendy L. Dixon occupies the position of Chairman at Sesen Bio, Inc. and President at Great Meadow Consulting LLC. She is also on the board of 5 other companies.
In her past career Dr. Dixon occupied the position of Principal at West Pharmaceutical Services, Inc., Senior Vice President & President-Marketing at Merck & Co., Inc., Chief Marketing Officer for Bristol-Myers Squibb Co., Principal at Centocor, Inc., Senior Advisor at The Monitor Group, Inc., Principal at Osteotech, Inc. and Principal at Smithkline & French Laboratories US, Inc.
She received a graduate degree, a doctorate and an undergraduate degree from the University of Cambridge.
|
Mark Jay Levin
|
Mr. Mark J. Levin is a Chairman at Voyager Therapeutics, Inc., a Partner at Third Rock Ventures LLC, a Chairman at Fulcrum Therapeutics, Inc., a Managing Member at TRV GP LLC, a Member at National Academy of Engineering and a Member at Personalized Medicine Coalition. He is on the Board of Directors at Corvia Medical, Inc., NinePoint Medical, Inc. and Partners In Health.
Mr. Levin was previously employed as an Independent Director by Foundation Medicine, Inc., a Chief Executive Officer & Director by Millennium Pharmaceuticals, Inc., a Chief Executive Officer by Focal, Inc., a Chief Executive Officer by Tularik, Inc., a Chief Executive Officer by CytoTherapuetics, Inc., a Chief Executive Officer by StemCells, Inc., a Chief Executive Officer by Cell Genesys, Inc., a Partner by Mayfield Fund LLC, a Chief Executive Officer by Abgenix, Inc., a Chairman by Constellation Pharmaceuticals, Inc., a Process Engineer & Project Leader by Eli Lilly & Co., and a Process Engineer & Project Leader by Genentech, Inc. He also served on the board at Blueprint Medicines Corp. and Eleven Biotherapeutics, Inc.
He received his graduate degree from Washington University in St. Louis.
|
Michael John Higgins
|
Michael John Higgins is on the board of Genocea Biosciences, Inc. and 5 other companies.
In his past career he was Chief Operating Officer for Ironwood Pharmaceuticals, Inc., Chief Financial Officer for Boston Business Journal, Group Vice President at Jacobs Engineering Group, Inc. and Director & Vice President at Jacobs One Ltd. (a subsidiary of Jacobs Engineering Group, Inc.), Vice President-Finance & Business Development at Genzyme Corp. and Chief Financial Officer of Procept, Inc.
Mr. Higgins received an undergraduate degree from Cornell University, an MBA from Tuck School of Business at Dartmouth and a graduate degree from Dartmouth College.
|
交易日期 | 交易人 | 职位 | 类型 | 交易份额 | 价格 |
---|---|---|---|---|---|
2018-04-09
|
Ravina (Bernard M.D.)
|
Officer
|
Sell
|
2451
|
18.38
|
2018-04-09
|
Ravina (Bernard M.D.)
|
Officer
|
Sell
|
2451
|
18.38
|
2018-03-22
|
Henderson (Jane V)
|
Officer
|
Buy
|
11200
|
11.97
|
2018-03-22
|
Henderson (Jane V)
|
Officer
|
Sell
|
11200
|
20.52
|
2018-03-22
|
Henderson (Jane V)
|
Officer
|
Sell
|
11200
|
20.52
|
2018-03-22
|
Henderson (Jane V)
|
Officer
|
Buy
|
11200
|
11.97
|
2018-03-21
|
Henderson (Jane V)
|
Officer
|
Buy
|
19900
|
11.97
|
2018-03-21
|
Henderson (Jane V)
|
Officer
|
Sell
|
19900
|
21.07
|
2018-03-21
|
Henderson (Jane V)
|
Officer
|
Buy
|
19900
|
11.97
|
2018-03-21
|
Henderson (Jane V)
|
Officer
|
Sell
|
19900
|
21.07
|
2018-03-18
|
Henderson (Jane V)
|
Officer
|
Buy
|
1900
|
11.97
|
2018-03-18
|
Henderson (Jane V)
|
Officer
|
Buy
|
1900
|
11.97
|
2018-03-18
|
Henderson (Jane V)
|
Officer
|
Sell
|
1900
|
21.76
|
2018-03-18
|
Henderson (Jane V)
|
Officer
|
Sell
|
1900
|
21.76
|
2018-03-15
|
Henderson (Jane V)
|
Officer
|
Buy
|
15416
|
11.97
|
2018-03-15
|
Henderson (Jane V)
|
Officer
|
Sell
|
15416
|
22.15
|
2018-03-15
|
Henderson (Jane V)
|
Officer
|
Sell
|
15416
|
22.15
|
2018-03-15
|
Henderson (Jane V)
|
Officer
|
Buy
|
15416
|
11.97
|
2018-03-11
|
Ravina (Bernard M.D.)
|
Officer
|
Sell
|
2451
|
25.16
|
2018-03-11
|
Ravina (Bernard M.D.)
|
Officer
|
Sell
|
2451
|
25.16
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
4376
|
8.33
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
5000
|
11.09
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
2184
|
7.27
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Sell
|
15623
|
30.00
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
4063
|
11.83
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
5000
|
11.09
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
2184
|
7.27
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Sell
|
15623
|
30.00
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
4063
|
11.83
|
2018-02-26
|
Sah (Dinah)
|
Officer
|
Buy
|
4376
|
8.33
|
持有者 | 持有份额 | 持股比例 | 份额变化 | 变化率 | 报告日期 |
---|---|---|---|---|---|
LAURION CAPITAL MANAGEMENT LP
|
288963
|
--
|
-173942
|
-37.58%
|
2018-03-31
|
Vanguard Group Inc
|
1083152
|
--
|
136057
|
14.37%
|
2018-06-30
|
Casdin Capital, LLC
|
1135000
|
--
|
--
|
--
|
2018-06-30
|
State Street Corp
|
1229912
|
--
|
430966
|
53.94%
|
2018-06-30
|
BlackRock Inc
|
1245322
|
--
|
196509
|
18.74%
|
2018-06-30
|
Fidelity Management and Research Company
|
1686862
|
--
|
-1600189
|
-48.68%
|
2018-07-31
|
BB Biotech AG
|
2532641
|
--
|
540000
|
27.10%
|
2018-06-30
|
Bellevue Asset Management AG
|
2532641
|
--
|
540000
|
27.10%
|
2018-06-30
|
Third Rock Ventures, LLC
|
18795473
|
--
|
8484297
|
82.28%
|
2017-12-31
|
Highline Capital Management LLC
|
840670
|
--
|
840670
|
--
|
2018-06-30
|
Farallon Capital Management, L.L.C.
|
768157
|
--
|
-121843
|
-13.69%
|
2018-06-30
|
Great Point Partners LLC
|
730010
|
--
|
730010
|
--
|
2018-06-30
|
UBS Asset Mgmt Americas Inc
|
327830
|
--
|
60728
|
22.74%
|
2018-06-30
|
Morgan Stanley & Co Inc
|
359635
|
--
|
-60357
|
-14.37%
|
2018-06-30
|
Wells Fargo Advisors, LLC
|
418222
|
--
|
37443
|
9.83%
|
2018-06-30
|
Adage Capital Partners Gp LLC
|
475000
|
--
|
--
|
--
|
2018-06-30
|
Wellington Management Company LLP
|
518354
|
--
|
18344
|
3.67%
|
2018-06-30
|
BlackRock Institutional Trust Company NA
|
600384
|
--
|
211168
|
54.25%
|
2018-06-30
|
Millennium Management LLC
|
619918
|
--
|
1897
|
0.31%
|
2018-06-30
|
Eventide Asset Management, LLC
|
703425
|
--
|
--
|
--
|
2018-06-30
|
Renaissance Technologies Corp
|
211565
|
--
|
211565
|
--
|
2018-03-31
|
AllianceBernstein LP
|
283830
|
--
|
-65677
|
-18.79%
|
2018-03-31
|
AXA Investment Managers UK Ltd
|
239190
|
--
|
-32282
|
-11.89%
|
2018-04-30
|
Tourbillon Capital Partners LP
|
230000
|
--
|
230000
|
--
|
2017-12-31
|
Altrinsic Global Advisors LLC
|
264927
|
--
|
100000
|
60.63%
|
2017-12-31
|
Arctic Fund Management AS
|
146201
|
--
|
--
|
--
|
2018-02-28
|
Northern Trust Investments N A
|
194102
|
--
|
40606
|
26.45%
|
2017-12-31
|
Point72 Asset Management, L.P.
|
130900
|
0.50%
|
130900
|
--
|
2017-09-30
|
Geode Capital Management, LLC
|
172673
|
0.55%
|
31248
|
22.10%
|
2017-12-31
|
Citadel Advisors Llc
|
250384
|
0.95%
|
250384
|
--
|
2017-09-30
|
Partner Fund Management LP
|
397923
|
1.52%
|
-455202
|
-53.36%
|
2017-09-30
|
Dafna Capital Management LLC
|
157000
|
0.50%
|
39741
|
33.89%
|
2017-12-31
|
Baker Bros Advisors LP
|
237014
|
0.90%
|
237014
|
--
|
2017-09-30
|
Deerfield Management Co
|
117647
|
0.45%
|
--
|
--
|
2017-09-30
|
Fiduciary Trust Co
|
109034
|
0.42%
|
--
|
--
|
2017-09-30
|
BlackRock Fund Advisors
|
939469
|
3.46%
|
-5005
|
-0.53%
|
2017-12-28
|
Dimensional Fund Advisors, Inc.
|
105914
|
0.40%
|
7786
|
7.93%
|
2017-09-30
|
Bridgeway Capital Management, Inc
|
70000
|
0.27%
|
70000
|
--
|
2017-09-30
|
Sanofi
|
2477941
|
9.94%
|
2477941
|
--
|
2015-12-31
|
Brookside Capital Management LLC
|
1514082
|
5.96%
|
--
|
--
|
2016-09-30
|
Goldman Sachs Asset Management LP
|
594422
|
2.34%
|
-94823
|
-13.76%
|
2016-09-30
|
J.P. Morgan Investment Management Inc
|
162003
|
0.64%
|
-74922
|
-31.62%
|
2016-09-30
|
GlobeFlex Capital, L.P.
|
90631
|
0.36%
|
50401
|
125.28%
|
2016-09-30
|
Ascend Capital LLC
|
58267
|
0.23%
|
58267
|
--
|
2016-09-30
|
J. P. Morgan Chase Bank NA
|
49197
|
0.19%
|
-2303
|
-4.47%
|
2016-09-30
|
Funds affiliated with Fidelity Management Research Company
|
1568626
|
11.00%
|
--
|
0.10%
|
1999-11-30
|
Aventis, Inc.
|
2352941
|
11.00%
|
--
|
0.10%
|
1999-11-30
|
Third Rock Ventures, L.P.
|
11061176
|
11.00%
|
--
|
0.40%
|
1999-11-30
|
持有者 | 持有份额 | 持股比例 | 份额变化 | 变化率 | 报告日期 |
---|---|---|---|---|---|
AST Prudential Growth Allocation Port
|
48900
|
0.15%
|
--
|
--
|
2018-07-31
|
Eventide Healthcare & Life Sciences A
|
703425
|
2.19%
|
--
|
--
|
2018-06-30
|
Vanguard Total Stock Mkt Idx
|
540453
|
1.69%
|
--
|
--
|
2018-07-31
|
iShares Nasdaq Biotechnology
|
365766
|
0.97%
|
-696
|
-0.19%
|
2018-09-12
|
Vanguard Extended Market Idx Inv
|
261183
|
0.81%
|
--
|
--
|
2018-07-31
|
iShares Russell 2000 Growth
|
203463
|
0.54%
|
-196
|
-0.10%
|
2018-09-12
|
JPMorgan US Small Company Instl
|
188300
|
0.59%
|
3700
|
2.00%
|
2018-07-31
|
AST Small-Cap Growth
|
152147
|
0.47%
|
39317
|
34.85%
|
2018-07-31
|
Fidelity Advisor
|
92133
|
0.29%
|
-634526
|
-87.32%
|
2018-07-31
|
Fidelity Spartan
|
91674
|
0.29%
|
--
|
--
|
2018-07-31
|
Bridgeway Ultra-Small Company Market
|
70000
|
0.22%
|
--
|
--
|
2018-06-30
|
CREF Stock R1
|
71418
|
0.22%
|
-1094
|
-1.51%
|
2018-07-31
|
Vanguard Explorer Inv
|
61401
|
0.19%
|
61401
|
--
|
2018-06-30
|
ALPS Medical Breakthroughs ETF
|
58876
|
0.16%
|
--
|
--
|
2018-09-14
|
ClearBridge Small Cap Value A
|
65400
|
0.18%
|
--
|
--
|
2018-06-30
|
iShares Micro-Cap
|
57782
|
0.15%
|
--
|
--
|
2018-09-12
|
Schwab US Small-Cap ETF
|
54912
|
0.15%
|
--
|
--
|
2018-09-13
|
Northern Trust Russell 2000 Index Fund - DC - Non-Lending
|
51994
|
0.16%
|
9
|
0.02%
|
2018-07-31
|
SPDR
|
910988
|
2.53%
|
-8040
|
-0.87%
|
2018-09-13
|
Fidelity
|
1605562
|
5.01%
|
--
|
--
|
2018-07-31
|
Vanguard Health Care ETF
|
41143
|
0.13%
|
80
|
0.19%
|
2018-06-30
|
Schwab Small Cap Index
|
40000
|
0.12%
|
7600
|
23.46%
|
2018-06-30
|
The Vanguard Russell 2000 Growth Index
|
37964
|
0.12%
|
37964
|
--
|
2018-06-30
|
BioShares
|
37502
|
0.12%
|
--
|
--
|
2018-07-06
|
iShares Russell 2000 Value
|
164368
|
0.55%
|
212
|
0.13%
|
2018-06-14
|
DFA US Micro Cap I
|
29343
|
0.09%
|
--
|
--
|
2018-02-28
|
DFA US Small Cap I
|
34658
|
0.11%
|
--
|
--
|
2018-02-28
|
Vanguard Instl Ttl Stk Mkt Idx InstlPls
|
34952
|
0.11%
|
--
|
--
|
2018-02-28
|
RS Technology A
|
38370
|
0.12%
|
38370
|
--
|
2017-12-31
|
BlackRock Russell 2000
|
28441
|
0.09%
|
8066
|
39.59%
|
2017-12-31
|
AXA 2000 Managed Volatility K
|
22435
|
0.09%
|
--
|
--
|
2017-10-31
|
BlackRock Russell 2500
|
24527
|
0.09%
|
13184
|
116.23%
|
2017-09-30
|
PowerShares DWA SmallCap Momentum ETF
|
48370
|
0.18%
|
--
|
--
|
2017-12-28
|
Russell US Small Cap Equity I
|
14909
|
0.06%
|
--
|
--
|
2016-12-31
|
Met Invt Ser JPMorgan Small Cap Val A
|
17600
|
0.07%
|
-3600
|
-16.98%
|
2016-12-31
|
VY JPMorgan Small Cap Core Equity S
|
20100
|
0.08%
|
-1800
|
-8.22%
|
2016-12-31
|
JPMorgan Small Cap Value A
|
66300
|
0.25%
|
--
|
--
|
2016-12-31
|
Goldman Sachs Small/Mid Cap Growth A
|
277284
|
1.04%
|
-292076
|
-51.30%
|
2016-12-31
|